Effect of foodstuffs on the absorption of zinc sulfate

Détails

ID Serval
serval:BIB_5F5CF638ED31
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Effect of foodstuffs on the absorption of zinc sulfate
Périodique
Clinical Pharmacology and Therapeutics
Auteur⸱e⸱s
Pecoud  A., Donzel  P., Schelling  J. L.
ISSN
0009-9236 (Print)
Statut éditorial
Publié
Date de publication
04/1975
Volume
17
Numéro
4
Pages
469-74
Notes
Clinical Trial
Journal Article --- Old month value: Apr
Résumé
Single doses of zinc sulfate were given to healthy young volunteers, either in the fasting state or with various types of meals. Dairy products (milk and cheese) and brown bread decreased zinc absorption, as indicated by a significant drop in peak serum zinc levels. Zinc absorption was decreased when zinc was given in the fasting state with the same amounts of purified phosphate or phytate as those found in foods above. Experiments in vitro have shown that zinc is precipitated by phosphate and phytate at pH values close to that of the intestinal lumen. Coffee also seems to inhibit zinc absorption.
Mots-clé
Adult Calcium/pharmacology Clinical Trials Dairy Products Female *Food Humans Intestinal Absorption/drug effects Male Middle Aged Phosphates/pharmacology Phytic Acid/pharmacology Sulfates/metabolism Time Factors Zinc/adverse effects/*metabolism
Pubmed
Web of science
Création de la notice
28/01/2008 11:58
Dernière modification de la notice
20/08/2019 14:17
Données d'usage