Postmortem distribution of 3-beta-hydroxybutyrate.

Détails

ID Serval
serval:BIB_5EEFA2FECF2B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Postmortem distribution of 3-beta-hydroxybutyrate.
Périodique
Journal of Forensic Sciences
Auteur(s)
Palmiere C., Mangin P., Werner D.
ISSN
1556-4029 (Electronic)
ISSN-L
0022-1198
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
59
Numéro
1
Pages
161-166
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish Document Type: Article; Proceedings Paper PDF : Paper
Résumé
The concentrations of 3-beta-hydroxybutyrate (3HB) in femoral blood, urine, vitreous humor as well as pericardial and cerebrospinal fluids were retrospectively examined in a series of medico-legal autopsies, which included cases of diabetic ketoacidosis, hypothermia fatalities without ethanol in blood, bodies presenting mild decompositional changes, and sudden deaths in chronic alcoholics. Similar increases in 3HB concentrations were observed in blood, vitreous, and pericardial fluid, irrespective of the cause of death, suggesting that pericardial fluid and vitreous can both be used as alternatives to blood for postmortem 3HB determination. Urine 3HB levels were higher than blood values in most cases. Cerebrospinal fluid 3HB levels were generally lower than concentrations in blood and proved to be diagnostic of underlying metabolic disturbances only when significant increases occurred.
Pubmed
Web of science
Création de la notice
18/07/2014 19:10
Dernière modification de la notice
20/08/2019 15:16
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