Derivation and validation of a Short Form of the Mini-Mental State Examination for the screening of dementia in older adults with a memory complaint.

Détails

ID Serval
serval:BIB_5ED8C5484E1D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Derivation and validation of a Short Form of the Mini-Mental State Examination for the screening of dementia in older adults with a memory complaint.
Périodique
European journal of neurology
Auteur⸱e⸱s
Haubois G., de Decker L., Annweiler C., Launay C., Allali G., Herrmann F.R., Beauchet O.
ISSN
1468-1331 (Electronic)
ISSN-L
1351-5101
Statut éditorial
Publié
Date de publication
03/2013
Peer-reviewed
Oui
Volume
20
Numéro
3
Pages
588-590
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Validation Study
Publication Status: ppublish
Résumé
To validate a Short Form of the Mini-Mental State Examination (SMMSE) as a screening test for dementia in older ambulatory individuals followed in a memory clinic for a memory complaint.
A total of 202 cognitively healthy individuals, 100 individuals with a mild cognitive impairment and 304 demented individuals sent for a memory complaint by their primary care physician to a memory clinic were prospectively included in this cross-sectional study. They were randomized into derivation (n = 303) and validation (n = 303) groups. The SMMSE score was built from six memory items of MMSE, with a score ranging from 0 to 6 (i.e. best performance).
The receiver operating characteristic curve showed an area under the curve of 0.98 for the derivation group and 0.97 for the validation group without differences between curves (P = 0.254). The cut-off between the sensitivity and the specificity of the SMMSE score for clinically diagnosed dementia was ≤4. The performance of the SMMSE for the diagnosis of dementia was high in the derivation and validation groups: sensitivity at 93.1% and 93.8%, specificity at 93.8% and 90.5%, positive predictive value at 94.3% and 90.1%, negative predictive value at 92.5% and 94.0%, likelihood ratio of positive test at 14.9 and 9.8 and of negative test at 0.07 and 0.07, respectively.
The Short Form of the Mini-Mental State Examination was a good screening test for dementia in older individuals followed in a memory clinic for a memory complaint. The next step should be the confirmation of its discriminative value in older primary care patients.
Mots-clé
Aged, Area Under Curve, Dementia/complications, Dementia/diagnosis, Female, Humans, Male, Mass Screening/methods, Memory Disorders/diagnosis, Memory Disorders/etiology, Neuropsychological Tests, ROC Curve, Sensitivity and Specificity
Pubmed
Web of science
Création de la notice
11/08/2023 13:49
Dernière modification de la notice
03/10/2023 5:58
Données d'usage