Prevention of vascular remodelling in cardiovascular disease

Détails

ID Serval
serval:BIB_5EC137F06722
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Prevention of vascular remodelling in cardiovascular disease
Périodique
Cardiology
Auteur(s)
Hayoz  D., Weber  R., Brunner  H. R.
ISSN
0008-6312 (Print)
Statut éditorial
Publié
Date de publication
1995
Volume
86 Suppl 1
Pages
23-9
Notes
Journal Article
Review
Résumé
The early detection of arterial wall transformations that may further evolve into atherosclerosis may help to identify high-risk patients among the hypertensive population and to select the most appropriate treatment. Intima-media layer thickening that affects a number of hypertensive subjects may potentially represent an indicator of accelerated atherosclerotic transformation of the vessel wall. Diagnosis and quantification of these early changes preceding plaque development should make it possible to determine whether antihypertensive treatment can restore normal wall structures in addition to normalizing the blood pressure. This article reviews some of the new approaches developed in our laboratory to assess both structure and function of conduit vessels. Preliminary data suggest that it is feasible to identify minute geometrical changes in hypertensive subjects long before major vascular lesions occur. This opens a whole new field of investigation into early arterial remodelling, a potential precursor of atherosclerosis.
Mots-clé
Adaptation, Physiological Arteries/*pathology/*physiopathology Arteriosclerosis/etiology Biomechanics Cardiovascular Diseases/*pathology/*physiopathology Clinical Trials Humans Risk Factors
Pubmed
Web of science
Création de la notice
17/01/2008 17:38
Dernière modification de la notice
20/08/2019 15:16
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