In vivo NMR spectroscopy: investigation of brain metabolism in neonates and infants.

Détails

ID Serval
serval:BIB_5C68A8DB4561
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
In vivo NMR spectroscopy: investigation of brain metabolism in neonates and infants.
Périodique
Pédiatrie
Auteur(s)
Martin E., Grütter R., Boesch C.
ISSN
0929-693X
ISSN-L
0031-4021
Statut éditorial
Publié
Date de publication
1990
Volume
45
Numéro
10
Pages
677-682
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
Magnetic resonance imaging (MRI) is a noninvasive investigation technique that uses non ionizing radio waves of low quantum energy, rendering it suitable for application in children. Monitoring and anesthesia techniques allow MRL including immobilisation in a special incubator to be carried out in small infants. In vivo magnetic resonance spectroscopy (MRS) provides biochemical information on living organisms in a non-invasive manner. Such a technique has recently been used to study neonatal brain energy metabolism. High energy phosphate metabolism and phospholipid metabolism can be evaluated in this manner and available clinical correlations can be made regarding eg seizures or long term neurologic sequelae associated with a decreased phosphocreatine: orthophosphate ratio. Future trends in neonatal MRS will provide further information on morphologic and metabolic brain development.
Mots-clé
Aging/physiology, Brain/metabolism, Brain Diseases/metabolism, Energy Metabolism, Humans, Infant, Infant, Newborn, Magnetic Resonance Imaging, Phosphates/metabolism, Phospholipids/metabolism
Pubmed
Création de la notice
29/04/2013 9:41
Dernière modification de la notice
20/08/2019 14:14
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