Nouvelles thérapies en rhumatologie pédiatrique [New therapies in pediatric rheumatology].

Détails

ID Serval
serval:BIB_55E48DB2D309
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Nouvelles thérapies en rhumatologie pédiatrique [New therapies in pediatric rheumatology].
Périodique
Revue Médicale Suisse
Auteur(s)
Enders F.B., Von Scheven-Gête A., Vanoni F., Fonjallaz B., Hofer M.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
2012
Volume
8
Numéro
329
Pages
418-422
Langue
français
Notes
Publication types: English Abstract ; Journal ArticlePublication Status: ppublish
Résumé
Biotherapies are recent treatments, which target molecules implicated in the pathogenesis of inflammatory diseases. In pediatric rheumatology, we use anti-TNF-alpha and abatacept in JIA patients with polyarticular involvement, whereas anti-IL-6 and anti-IL-1 blockers are efficacious in the systemic form of JIA and other auto-inflammatory conditions. These new treatments have significantly improved the control of articular and systemic inflammation and the prognosis of rheumatic diseases. Their effect and their safety on the long-term need to be assessed on large cohorts of patients. Due to the impact of these chronic illnesses on the young patient and its family, and the required specific knowledge, the care of these children should be provided by a multidisciplinary team linked to a centre of competence.
Mots-clé
Biological Agents/therapeutic use, Child, Humans, Rheumatic Diseases/drug therapy
Pubmed
Création de la notice
06/06/2012 19:05
Dernière modification de la notice
20/08/2019 15:10
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