Arterial spin labeled carotid MR angiography: A phantom study examining the impact of technical and hemodynamic factors.

Détails

ID Serval
serval:BIB_55A2698205D3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Arterial spin labeled carotid MR angiography: A phantom study examining the impact of technical and hemodynamic factors.
Périodique
Magnetic Resonance In Medicine
Auteur(s)
Koktzoglou I., Giri S., Piccini D., Grodzki D.M., Flanagan O., Murphy I.G., Gupta N., Collins J.D., Edelman R.R.
ISSN
1522-2594 (Electronic)
ISSN-L
0740-3194
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
75
Numéro
1
Pages
295-301
Langue
anglais
Résumé
PURPOSE: To quantify the accuracy of three-dimensional (3D) radial arterial spin labeled (ASL) magnetic resonance angiography (MRA) using vascular models of carotid stenosis.
METHODS: Eight vascular models were imaged at 1.5 Tesla using pulsatile flow waveforms at rates found in the internal carotid arteries (100-400 mL/min). The impacts of the 3D ASL imaging readout (fast low angle shot (FLASH) versus balanced steady-state free precession (bSSFP)), ultrashort echo time imaging using a pointwise encoding time reduction with radial acquisition (PETRA), and model stenosis severity on the accuracy of vascular model display at the location of stenosis were quantified. Accuracy was computed vis-à-vis a reference bSSFP volume acquired under no flow. Comparisons were made with standard-of-care contrast-enhanced MRA (CEMRA) and Cartesian time-of-flight (TOF) MRA protocols.
RESULTS: For 50% and 70% stenoses, CEMRA was most accurate (respective accuracies of 81.7% and 78.6%), followed by ASL FLASH (75.7% and 71.8%), ASL PETRA (69.6% and 70.6%), 3D TOF (66.6% and 57.1%), ASL bSSFP (68.7% and 51.2%), and 2D TOF (65.1% and 50.6%).
CONCLUSION: Flow phantom imaging studies show that ASL MRA can improve the display of hemodynamically significant carotid arterial stenosis compared with TOF MRA, with FLASH and ultrashort echo time readouts being most accurate. Magn Reson Med 75:295-301, 2016. © 2015 Wiley Periodicals, Inc.
Pubmed
Web of science
Création de la notice
02/02/2016 18:34
Dernière modification de la notice
20/08/2019 15:10
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