Etude suisse sur la pollution de l'air et les maladies respiratoires chez l'adulte (SAPALDIA). Swiss Study on Air Pollution and Lung Diseases in Adults. [Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA)]

Détails

ID Serval
serval:BIB_53B51F91CCEE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Etude suisse sur la pollution de l'air et les maladies respiratoires chez l'adulte (SAPALDIA). Swiss Study on Air Pollution and Lung Diseases in Adults. [Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA)]
Périodique
Schweizerische Medizinische Wochenschrift
Auteur⸱e⸱s
Leuenberger  P., Kunzli  N., Ackermann-Liebrich  U., Schindler  C., Bolognini  G., Bongard  J. P., Brandli  O., Defila  C., Domenighetti  G., Karrer  W., Keller  R., Medici  T., Monn  C., Perruchoud  A. P., Schoni  M., Tschopp  J. M., Villiger  B., Wuthrich  B., Zellweger  J. P.
ISSN
0036-7672 (Print)
Statut éditorial
Publié
Date de publication
01/1998
Volume
128
Numéro
5
Pages
150-61
Notes
English Abstract
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jan 31
Résumé
Long-term health effects of moderate ambient air pollution are rarely investigated. In Switzerland, no large-scale study has addressed this issue so far. Important results of the Swiss Study on Air Pollution and Lung Disease in Adults (SAPALDIA) are presented. During the period 1991-1993, SAPALDIA investigated a random population sample (18-60 years) in eight Swiss areas with different environmental characteristics (Aarau, Basel, Davos, Geneva, Lugano, Montana, Payerne, Wald). In total, 9651 adults (60%) participated in the cross-sectional investigation (part 1, 1991), consisting of the following standardized procedures: questionnaire (interview), forced expiratory lung function test, bronchial challenge with methacholine, atopy assessment (Phadiatop, unspecific total IgE), allergy skin tests, and endexpiratory CO-measurements. Subjects with a history of respiratory symptoms, increased bronchial reactivity, reduced lung function (FEV1/FVC < 80% predicted) and 150 healthy never-smokers were included in the subsequent diary study (part 2; n = 3281, 1992/93). Peak flow (morning and evening), symptoms, medication, personal activity and visits to the doctor were monitored. Across regions, annual mean values ranged from 9 to 52 mg/m3 (NO2) and 10 to 33 mg/m3 (PM10) respectively. Air pollution had effects on prevalence of dyspnea (+41% per 10 mg/m3 increment of the annual mean PM10, 95% CI 20-65%), on symptoms of chronic bronchitis (+31%, 10-55%), on FVC (-3.1%; -3.7 to -2.6%), and FEV1 (-1.1%; -1.7% to -0.5%), on the incidence of respiratory symptoms and the length of symptomfree intervals (11% change per 10 mg/m3 PM10), but not on the prevalence of asthma. Environmental tobacco smoke (ETS) showed impact on wheezing (OR 1.94; 1.39-2.70), asthma (1.39; 1.04-1.86), bronchitis (1.60; 1.24-2.08) and chronic bronchitis (1.50; 1.11-2.02). Health effects of moderate air pollution were confirmed in Switzerland. Although for the individual the relative risks are small, the public health impact may be considerable. An ongoing follow-up will investigate the mortality profile of the SAPALDIA cohort.
Mots-clé
Adolescent Adult Air Pollution/*adverse effects/statistics & numerical data Bronchial Provocation Tests Cross-Sectional Studies Female Forced Expiratory Volume Humans Lung Diseases/epidemiology/*etiology Lung Diseases, Obstructive/epidemiology/etiology Male Middle Aged Population Surveillance Risk Switzerland/epidemiology
Pubmed
Web of science
Création de la notice
25/01/2008 9:50
Dernière modification de la notice
20/08/2019 14:08
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