Association of the Interaction Between Smoking and Depressive Symptom Clusters With Coronary Artery Calcification: The CARDIA Study.

Détails

ID Serval
serval:BIB_53864139D2F7
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Association of the Interaction Between Smoking and Depressive Symptom Clusters With Coronary Artery Calcification: The CARDIA Study.
Périodique
Journal of dual diagnosis
Auteur⸱e⸱s
Carroll A.J., Auer R., Colangelo L.A., Carnethon M.R., Jacobs D.R., Stewart J.C., Widome R., Carr J.J., Liu K., Hitsman B.
ISSN
1550-4271 (Electronic)
ISSN-L
1550-4271
Statut éditorial
Publié
Date de publication
2017
Peer-reviewed
Oui
Volume
13
Numéro
1
Pages
43-51
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Depressive symptom clusters are differentially associated with prognosis among patients with cardiovascular disease (CVD). Few studies have prospectively evaluated the association between depressive symptom clusters and risk of CVD. Previously, we observed that smoking and global depressive symptoms were synergistically associated with coronary artery calcification (CAC). The purpose of this study was to determine whether the smoking by depressive symptoms interaction, measured cumulatively over 25 years, differed by depressive symptom cluster (negative affect, anhedonia, and somatic symptoms) in association with CAC.
Participants (N = 3,189: 54.5% female; 51.5% Black; average age = 50.1 years) were followed from 1985-1986 through 2010-2011 in the Coronary Artery Risk Development in Young Adults (CARDIA) study. Smoking exposure was measured by cumulative cigarette pack-years (cigarette packs smoked per day × number of years smoking; year 0 through year 25). Depressive symptoms were measured using a 14-item, 3-factor (negative affect, anhedonia, somatic symptoms) model of the Center for Epidemiologic Studies Depression (CES-D) Scale (years 5, 10, 15, 20, and 25). CAC was assessed at year 25. Logistic regression models were used to evaluate the association between the smoking by depressive symptom clusters interactions with CAC ( = 0 vs. > 0), adjusted for CVD-related sociodemographic, behavioral, and clinical covariates.
907 participants (28% of the sample) had CAC > 0 at year 25. The depressive symptom clusters did not differ significantly between the two groups. Only the cumulative somatic symptom cluster by cumulative smoking exposure interaction was significantly associated with CAC > 0 at year 25 (p = .028). Specifically, adults with elevated somatic symptoms (score 9 out of 18) who had 10, 20, or 30 pack-years of smoking exposure had respective odds ratios (95% confidence intervals) of 2.06 [1.08, 3.93], 3.71 [1.81, 7.57], and 6.68 [2.87, 15.53], ps < .05. Negative affect and anhedonia did not significantly interact with smoking exposure associated with CAC >0, ps > .05.
Somatic symptoms appear to be a particularly relevant cluster of depressive symptomatology in the relationship between smoking and CVD risk.

Mots-clé
African Americans, Coronary Artery Disease/complications, Coronary Artery Disease/epidemiology, Coronary Artery Disease/psychology, Depression/complications, Depression/epidemiology, European Continental Ancestry Group, Female, Humans, Male, Middle Aged, Smoking/adverse effects, Smoking/epidemiology, Smoking/psychology, Vascular Calcification/complications, Vascular Calcification/epidemiology, Vascular Calcification/psychology, Depression, cardiovascular disease risk, coronary artery calcification, depressive symptom clusters, prospective study, smoking, somatic symptoms
Pubmed
Web of science
Création de la notice
07/02/2017 18:31
Dernière modification de la notice
20/08/2019 14:08
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