Nanomechanics of microtubules.
Détails
ID Serval
serval:BIB_5281BE5CA0B6
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Nanomechanics of microtubules.
Périodique
Physical Review Letters
ISSN
0031-9007
Statut éditorial
Publié
Date de publication
12/2002
Peer-reviewed
Oui
Volume
89
Numéro
24
Pages
248101
Langue
anglais
Notes
Publication types: Journal Article
Résumé
We have determined the mechanical anisotropy of a single microtubule by simultaneously measuring the Young's and the shear moduli in vitro. This was achieved by elastically deforming the microtubule deposited on a substrate tailored by electron-beam lithography with a tip of an atomic force microscope. The shear modulus is 2 orders of magnitude lower than the Young's, giving rise to a length-dependent flexural rigidity of microtubules. The temperature dependence of the microtubule's bending stiffness in the (5-40) degrees C range shows a strong variation upon cooling coming from the increasing interaction between the protofilaments.
Mots-clé
Anisotropy, Elasticity, Microscopy, Atomic Force, Microtubules/chemistry, Microtubules/physiology, Nanotechnology/methods
Pubmed
Web of science
Création de la notice
24/01/2008 15:24
Dernière modification de la notice
20/08/2019 15:07