Hypothermia Outcome Prediction after Extracorporeal Life Support for Hypothermic Cardiac Arrest Patients: Assessing the Performance of the HOPE Score in Case Reports from the Literature.

Détails

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Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_51BE54685449
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Hypothermia Outcome Prediction after Extracorporeal Life Support for Hypothermic Cardiac Arrest Patients: Assessing the Performance of the HOPE Score in Case Reports from the Literature.
Périodique
International journal of environmental research and public health
Auteur⸱e⸱s
Grin N., Rousson V., Darocha T., Hugli O., Carron P.N., Zingg T., Pasquier M.
ISSN
1660-4601 (Electronic)
ISSN-L
1660-4601
Statut éditorial
Publié
Date de publication
12/11/2021
Peer-reviewed
Oui
Volume
18
Numéro
22
Pages
11896
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
Publication Status: epublish
Résumé
Aims: The hypothermia outcome prediction after extracorporeal life support (ECLS) score, or HOPE score, provides an estimate of the survival probability in hypothermic cardiac arrest patients undergoing ECLS rewarming. The aim of this study was to assess the performance of the HOPE score in case reports from the literature. Methods: Cases were identified through a systematic review of the literature. We included cases of hypothermic cardiac arrest patients rewarmed with ECLS and not included in the HOPE derivation and validation studies. We calculated the survival probability of each patient according to the HOPE score. Results: A total of 70 patients were included. Most of them (62/70 = 89%) survived. The discrimination using the HOPE score was good (Area Under the Receiver Operating Characteristic Curve = 0.78). The calibration was poor, with HOPE survival probabilities averaging 54%. Using a HOPE survival probability threshold of at least 10% as a decision criterion for rewarming a patient would have resulted in only five false positives and a single false negative, i.e., 64 (or 91%) correct decisions. Conclusions: In this highly selected sample, the HOPE score still had a good practical performance. The selection bias most likely explains the poor calibration found in the present study, with survivors being more often described in the literature than non-survivors. Our finding underscores the importance of working with a representative sample of patients when deriving and validating a score, as was the case in the HOPE studies that included only consecutive patients in order to minimize the risk of publication bias and lower the risk of overly optimistic outcomes.
Mots-clé
Cardiopulmonary Resuscitation, Extracorporeal Membrane Oxygenation, Heart Arrest/therapy, Humans, Hypothermia/therapy, Retrospective Studies, Rewarming, ECMO, ECPR, accidental, cardiac arrest, hypothermia, potassium, publication bias, resuscitation, selection bias, triage
Pubmed
Web of science
Open Access
Oui
Création de la notice
17/11/2021 10:46
Dernière modification de la notice
21/11/2022 9:28
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