Hepatic arterial chemotherapy: role of angiography

Détails

ID Serval
serval:BIB_5070B14BBC64
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Hepatic arterial chemotherapy: role of angiography
Périodique
Radiology
Auteur⸱e⸱s
Cho  K. J., Andrews  J. C., Williams  D. M., Doenz  F., Guy  G. E.
ISSN
0033-8419
Statut éditorial
Publié
Date de publication
12/1989
Peer-reviewed
Oui
Volume
173
Numéro
3
Pages
783-91
Notes
Cho, K J
Andrews, J C
Williams, D M
Doenz, F
Guy, G E
United states
Radiology
Radiology. 1989 Dec;173(3):783-91. --- Old month value: Dec
Résumé
Hepatic arterial infusion chemotherapy increases the hepatic concentration of chemotherapeutic agents without increasing systemic toxicity. Both percutaneous (most commonly left transbrachial) and surgical approaches are currently used for infusion catheter placement. Surgical catheter and pump placement has proved to be a reliable means of delivering drugs to the liver and has been commonly used for hepatic arterial chemotherapy for metastatic colorectal carcinoma. Meticulous angiographic evaluation of the hepatic vascular anatomy, its variations, and hemodynamics is necessary for correct catheter placement to achieve total liver perfusion without significant extrahepatic perfusion. Satisfactory hepatic perfusion should be documented before drug infusion. Hepatic arterial radionuclide flow imaging with technetium-99m-labeled macroaggregated serum albumin remains the most reliable means of assessing hepatic perfusion following catheter placement. Transcatheter techniques have been used to facilitate catheter placement, to prevent gastrointestinal drug toxicity, and to correct unsatisfactory perfusion following surgical catheter placement.
Mots-clé
Antineoplastic Agents/*administration & dosage Catheterization/methods Hemodynamics *Hepatic Artery/radiography Humans Infusion Pumps *Infusions, Intra-Arterial/adverse effects/methods Liver Circulation Liver Neoplasms/blood supply/*drug therapy
Pubmed
Web of science
Création de la notice
11/04/2008 11:46
Dernière modification de la notice
20/08/2019 14:06
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