Signal propagation via cortical hierarchies.

Détails

Ressource 1Télécharger: 33195949_BIB_501DF4B06243.pdf (2038.46 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_501DF4B06243
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Signal propagation via cortical hierarchies.
Périodique
Network neuroscience
Auteur⸱e⸱s
Vézquez-Rodríguez B., Liu Z.Q., Hagmann P., Misic B.
ISSN
2472-1751 (Electronic)
ISSN-L
2472-1751
Statut éditorial
Publié
Date de publication
2020
Peer-reviewed
Oui
Volume
4
Numéro
4
Pages
1072-1090
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Résumé
The wiring of the brain is organized around a putative unimodal-transmodal hierarchy. Here we investigate how this intrinsic hierarchical organization of the brain shapes the transmission of information among regions. The hierarchical positioning of individual regions was quantified by applying diffusion map embedding to resting-state functional MRI networks. Structural networks were reconstructed from diffusion spectrum imaging and topological shortest paths among all brain regions were computed. Sequences of nodes encountered along a path were then labeled by their hierarchical position, tracing out path motifs. We find that the cortical hierarchy guides communication in the network. Specifically, nodes are more likely to forward signals to nodes closer in the hierarchy and cover a range of unimodal and transmodal regions, potentially enriching or diversifying signals en route. We also find evidence of systematic detours, particularly in attention networks, where communication is rerouted. Altogether, the present work highlights how the cortical hierarchy shapes signal exchange and imparts behaviorally relevant communication patterns in brain networks.
Mots-clé
Brain connectivity, Connectome, Navigation, Neural communication, Neural networks
Pubmed
Web of science
Open Access
Oui
Création de la notice
23/11/2020 14:59
Dernière modification de la notice
12/01/2022 8:09
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