18F-FDG positive colorectal polyp mimicing metastasis of advanced melanoma treated with ipilimumab

Détails

ID Serval
serval:BIB_4F37351EC7B9
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
18F-FDG positive colorectal polyp mimicing metastasis of advanced melanoma treated with ipilimumab
Périodique
Nukleární medicína
Auteur(s)
Koukalová K., Lakomý R., Fabian P., Řehák Z., Szturz P.
ISSN
1805-1146
Statut éditorial
Publié
Date de publication
01/12/2019
Peer-reviewed
Oui
Volume
8
Numéro
4
Pages
76-79
Langue
tchèque
Résumé
Given its high diagnostic accuracy, 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) has often been used as initial staging and follow-up imaging in patients with malignant melanoma. In the majority of cases, the primary tumour and its metastases show high metabolic activity, and even small subclinical lesions can thus be detected by 18F-FDG PET/CT scanning. In 2010, an important step forward was made in the treatment of malignant melanoma – the era of modern immunotherapy began, and ipilimumab represented one of the first effective drugs. Herein, we present a case of a women with recurrent, metastatic melanoma with persistent increased 18F-FDG accumulation in the abdominal cavity. The lesion could not be identified on exploratory laparotomy and remained unchanged during ipilimumab treatment. Surprisingly, repeated PET/CT examination localized the FDG uptake to an asymptomatic colon polyp histologically corresponding to adenocarcinoma in situ arising in villous adenoma.
Mots-clé
PET/CT, immunotherapy, ipilimumab, colorectal polyp, carcinoma in situ
Création de la notice
06/12/2020 19:23
Dernière modification de la notice
07/12/2020 7:26
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