Choix des criteres positifs dans les tests de provocation bronchique specifiques avec un acarien purifie (Pharmalgen). [Choice of positive criteria in specific bronchial provocation tests with a purified acarian extract (Pharmalgen)]

Détails

ID Serval
serval:BIB_4F10B7E675ED
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Choix des criteres positifs dans les tests de provocation bronchique specifiques avec un acarien purifie (Pharmalgen). [Choice of positive criteria in specific bronchial provocation tests with a purified acarian extract (Pharmalgen)]
Périodique
Schweizerische Medizinische Wochenschrift
Auteur⸱e⸱s
Nicod  L., Pecoud  A., Leuenberger  P.
ISSN
0036-7672 (Print)
Statut éditorial
Publié
Date de publication
12/1984
Volume
114
Numéro
48
Pages
1771-3
Notes
English Abstract
Journal Article --- Old month value: Dec 1
Résumé
Bronchial provocation tests (PT) were performed with a purified and standardized extract of the house dust mite Dermatophagoides pteronyssinus (D. ptero.) in an attempt to determine the most sensitive criteria of bronchospasm. Nineteen asthmatic patients with skin test and RAST positive for D. ptero. had a positive bronchial PT. More than 40% increase of Raw insp. simultaneously with dyspnea or wheezing was found in each patient, whereas only 6/19 had a 20% increase of FEV1. 47% of the patients had a slight to moderate late phase of bronchial obstruction. None of the 9 asthmatic patients with skin test and RAST negative for mites had bronchospasm. It is concluded that a 40% in Raw insp., combined with clinical signs of bronchospasm, is a sensitive, specific and safe method of determining the threshold of bronchial sensitivity to a standardized allergen.
Mots-clé
Allergens/*diagnostic use Antigens, Dermatophagoides Asthma/*immunology Bronchial Provocation Tests/*methods Humans Mites/*immunology
Pubmed
Web of science
Création de la notice
28/01/2008 11:59
Dernière modification de la notice
20/08/2019 14:04
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