Limb girdle muscular dystrophy type 2A (CAPN3): mapping using allelic association

Détails

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ID Serval
serval:BIB_4E60D66A8D1D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
UNIL/CHUV
Titre
Limb girdle muscular dystrophy type 2A (CAPN3): mapping using allelic association
Périodique
Human Heredity
Auteur⸱e⸱s
Lonjou  C., Collins  A., Beckmann  J., Allamand  V., Morton  N.
ISSN
0001-5652 (Print)
Statut éditorial
Publié
Date de publication
12/1998
Volume
48
Numéro
6
Pages
333-7
Notes
Journal Article --- Old month value: Nov-Dec
Résumé
Recently a graphical study of linkage disequilibrium around the CAPN3 locus failed to refine the 1.3-Mb interval suggested by haplotype sharing. On the contrary, the Malecot model as implemented in the ALLASS program maps CAPN3 within 3 kb of its true location (23 kb from the locus midpoint), overcoming identified problems with small samples, interrelated sibships, and short duration.
Mots-clé
*Alleles Calpain/*genetics Genes, Recessive Genetic Markers Humans *Isoenzymes Linkage Disequilibrium Models, Genetic *Muscle Proteins Muscular Dystrophies/*genetics Peptide Fragments/*genetics
OAI-PMH
oai:serval.unil.ch:BIB_4E60D66A8D1D
DOI
10.1159/000022825
Pubmed
9813455
Web of science
000076947700005
Création de la notice
25/01/2008 17:18
Dernière modification de la notice
20/08/2019 15:03
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