Models of sleep regulation in mammals.

Détails

ID Serval
serval:BIB_4E5C311A8663
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Models of sleep regulation in mammals.
Périodique
Journal of sleep research
Auteur(s)
Tobler I., Franken P., Trachsel L., Borbély A.A.
ISSN
1365-2869[electronic]
Statut éditorial
Publié
Date de publication
06/1992
Peer-reviewed
Oui
Volume
1
Numéro
2
Pages
125-127
Langue
anglais
Résumé
A brief overview of models on the regulation of sleep/waking or rest/activity is provided. Applications of the two-process model are illustrated in two species: The homeostatic facet of the model (Process S) was used to quantitatively simulate sleep in the rat and guinea pig. The model parameters were estimated for rat sleep by an optimization procedure. A close correspondence between the time course of slow-wave activity and Process S was obtained for both species under baseline conditions. Whereas in the rat a close fit was obtained also for the recovery period from sleep deprivation, some discrepancies were present in the guinea pig. It is concluded that the concept of sleep homeostasis that has been elaborated and formalized in the two-process model for human sleep, can also be applied to simulate sleep in other mammals.
Pubmed
Création de la notice
24/01/2008 15:31
Dernière modification de la notice
20/08/2019 14:03
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