Prevention des complications oculaires de l'herpes zoster ophtalmique par un traitement adequat d'acyclovir. [Prevention of ocular complications of herpes zoster ophthalmicus by adequate treatment with acyclovir]

Détails

ID Serval
serval:BIB_4D527503AF5D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Prevention des complications oculaires de l'herpes zoster ophtalmique par un traitement adequat d'acyclovir. [Prevention of ocular complications of herpes zoster ophthalmicus by adequate treatment with acyclovir]
Périodique
Klinische Monatsblatter fur Augenheilkunde
Auteur(s)
Borruat  F. X., Buechi  E. R., Piguet  B., Fitting  P., Zografos  L., Herbort  C. P.
ISSN
0023-2165 (Print)
Statut éditorial
Publié
Date de publication
05/1991
Volume
198
Numéro
5
Pages
358-60
Notes
English Abstract
Journal Article --- Old month value: May
Résumé
We compared the frequency of severe ocular complications secondary to Herpes Zoster Ophthalmicus (HZO) in 232 patients. They were divided into three groups: 1) patients without treatment (n = 164); 2) patients treated adequately (n = 48) with acyclovir (ACV; 5 x 800 mg/d orally and ophthalmic ointment 5 x /d for a minimum of 7 days, given within three days after skin eruption); and, 3) patients treated inadequately (n = 20) with ACV (only topical treatment, insufficient doses, interrupted treatment, delayed treatment). Patients with no treatment or with inadequate treatments showed the same frequency of severe ocular complications (21% (34/164) and 25% (5/20), respectively). In contrast, when adequate treatment of ACV was given complications occurred in only 4% (2/48) of cases. This study emphasizes the need for prompt (within three days after skin eruption) and adequate (5 x 800 mg/d for at least 7 days) treatment of ACV to prevent the severe complications of HZO.
Mots-clé
Acyclovir/*administration & dosage Adolescent Adult Aged Aged, 80 and over Child Dose-Response Relationship, Drug Drug Administration Schedule Female Herpes Zoster Ophthalmicus/complications/*drug therapy Humans Male Middle Aged Prospective Studies Retrospective Studies
Pubmed
Web of science
Création de la notice
28/01/2008 12:37
Dernière modification de la notice
20/08/2019 14:02
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