Sex, age, and cognitive correlates of asymmetries in thickness of the cortical mantle across the life span.

Détails

ID Serval
serval:BIB_4C9C32778191
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Sex, age, and cognitive correlates of asymmetries in thickness of the cortical mantle across the life span.
Périodique
The Journal of neuroscience
Auteur⸱e⸱s
Plessen K.J., Hugdahl K., Bansal R., Hao X., Peterson B.S.
ISSN
1529-2401 (Electronic)
ISSN-L
0270-6474
Statut éditorial
Publié
Date de publication
30/04/2014
Peer-reviewed
Oui
Volume
34
Numéro
18
Pages
6294-6302
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
We assessed the correlations of age, sex, and cognitive performance with measures of asymmetry in cortical thickness on high-resolution MRIs in 215 healthy human children and adults, 7-59 years of age. A left > right asymmetry in thickness of the cortical mantle was present throughout the entire lateral, dorsal, and mesial surfaces of the frontal lobe, extending into primary sensory, superior parietal, and anterior superior temporal cortices. A right > left asymmetry was present in the lateral, mesial, and dorsal surfaces of the posterior temporal, parietal, and occipital cortices, as well as in the entire inferior surface of the brain. An exaggerated left > right asymmetry was detected in females in anterior brain regions, and an exaggerated right > left asymmetry was detected in males in the orbitofrontal, inferior parietal, and inferior occipital cortices. Weaker moderating effects of sex were scattered along the mesial surface of the brain. Age significantly moderated asymmetry measures in the inferior sensorimotor, inferior parietal, posterior temporal, and inferior occipital cortices. The age × asymmetry interaction derived from a steeper decline in cortical thickness with age in the right hemisphere than in the left on the lateral surface, whereas it derived from a steeper decline with age in the left hemisphere than in the right on the mesial surface. Finally, measures of performance on working memory and vocabulary tasks improved with increasing magnitudes of normal asymmetries in regions thought to support these cognitive capacities.
Mots-clé
Adolescent, Adult, Aging, Brain Mapping, Cerebral Cortex/anatomy & histology, Cerebral Cortex/physiology, Child, Cognition/physiology, Echo-Planar Imaging, Female, Functional Laterality/physiology, Humans, Imaging, Three-Dimensional, Magnetic Resonance Imaging, Male, Middle Aged, Neuropsychological Tests, Sex Characteristics, Young Adult, asymmetry, cognitive performance, cortical thickness
Pubmed
Création de la notice
14/02/2019 9:29
Dernière modification de la notice
20/08/2019 14:01
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