Disentangling reasons for low Y chromosome variation in the greater white-toothed shrew (Crocidura russula).
Détails
ID Serval
serval:BIB_4C47400D55BA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Disentangling reasons for low Y chromosome variation in the greater white-toothed shrew (Crocidura russula).
Périodique
Genetics
ISSN
0016-6731[print], 0016-6731[linking]
Statut éditorial
Publié
Date de publication
06/2006
Peer-reviewed
Oui
Volume
173
Numéro
2
Pages
935-942
Langue
anglais
Notes
Publication types: In Vitro ; Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
Y chromosome variation is determined by several confounding factors including mutation rate, effective population size, demography, and selection. Disentangling these factors is essential to better understand the evolutionary properties of the Y chromosome. We analyzed genetic variation on the Y chromosome, X chromosome, and mtDNA of the greater white-toothed shrew, a species with low variance in male reproductive success and limited sex-biased dispersal, which enables us to control to some extent for life-history effects. We also compared ancestral (Moroccan) to derived (European) populations to investigate the role of demographic history in determining Y variation. Recent colonization of Europe by a small number of founders (combined with low mutation rates) is largely responsible for low diversity observed on the European Y and X chromosomes compared to mtDNA. After accounting for mutation rate, copy number, and demography, the Y chromosome still displays a deficit in variation relative to the X in both populations. This is possibly influenced by directional selection, but the slightly higher variance in male reproductive success is also likely to play a role, even though the difference is small compared to that in highly polygynous species. This study illustrates that demography and life-history effects should be scrutinized before inferring strong selective pressure as a reason for low diversity on the Y chromosome.
Mots-clé
Animals, DNA, Mitochondrial/genetics, Europe, Evolution, Molecular, Female, Founder Effect, Gene Dosage, Genetic Variation, Genetics, Population, Haplotypes, Morocco, Mutation, Recombination, Genetic, Selection, Genetic, Shrews/genetics, X Chromosome/genetics, Y Chromosome/genetics
Pubmed
Web of science
Open Access
Oui
Création de la notice
24/01/2008 18:54
Dernière modification de la notice
20/08/2019 15:00