Cardiovascular diseases (CVD) remain a major cause of morbidity and mortality in industrialized countries. However, little attention is done on disability associated with CVD. Objectives: The objective of this study was to evaluate the trends of disability linked to CVD during these last 20 years in Switzerland. Based on medical publications and official Swiss statistics, CVD accounted for only 2.3% among all medical causes of sickness certification for >6 days established by primary care physicians in patients aged 15 to 64 years. Furthermore in 2006, CVD were involved only in 2.5% of women and 5.5% of men receiving a pension of Swiss disability insurance. Between 1987 and 2006, the proportion of diagnosis of CVD at medical office decreased from 14.6 to 12.4% (-15%), while during the same period, the reduction of the proportion of disability pension was more pronounced, from 9.6 to 4.1% (-57%). Conclusion: These results demonstrate that, despite the large number of CVD in Swiss population and the progressive increase of disability pensions for all causes during the last 20 years, a significant reduction of disability pensions due to CVD, and consequently result in large decrease of health costs among active population.