Chromosome size differences may affect meiosis and genome size.

Détails

Ressource 1Télécharger: BIB_49D879C420D8.P001.pdf (129.23 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_49D879C420D8
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Chromosome size differences may affect meiosis and genome size.
Périodique
Science
Auteur(s)
Wang J., Chen P.J., Wang G.J., Keller L.
ISSN
1095-9203[electronic], 0036-8075[linking]
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
329
Numéro
5989
Pages
293
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish
Résumé
Genetic crosses in many organisms have shown that alleles of unlinked genes generally assort independently of one another during gamete formation. However, variation in chromosome size may affect the process of meiosis and lead to nonindependent assortment of chromosomes. We therefore examined chromosomes with insertions and found that they preferentially segregated away from the X chromosome during meiosis in Caenorhabditis elegans males. Conversely, chromosomes with deletions preferentially segregated with the X chromosome. The degree of segregation bias was significantly associated with the length of the insertion or deletion. Simulations revealed that this segregation bias leads to genome size reduction in hermaphroditic species, a pattern consistent with differences in genome sizes in the genus Caenorhabditis. These results suggest that insertions and deletions may affect chromosome segregation patterns.
Pubmed
Web of science
Open Access
Oui
Création de la notice
27/05/2010 18:04
Dernière modification de la notice
20/08/2019 14:57
Données d'usage