Incidence of human granulocytic anaplasmosis in returning travellers with fever.

Détails

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Etat: Public
Version: Final published version
Licence: Non spécifiée
ID Serval
serval:BIB_464C421AD666
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Incidence of human granulocytic anaplasmosis in returning travellers with fever.
Périodique
Journal of travel medicine
Auteur(s)
Camprubí-Ferrer D., Portillo A., Santibáñez S., Almuedo-Riera A., Rodriguez-Valero N., Subirà C., Martinez M.J., Navero-Castillejos J., Fernandez-Pardos M., Genton B., Cobuccio L., Van Den Broucke S., Bottieau E., Muñoz J., Oteo J.A.
ISSN
1708-8305 (Electronic)
ISSN-L
1195-1982
Statut éditorial
Publié
Date de publication
01/06/2021
Peer-reviewed
Oui
Volume
28
Numéro
4
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Although tick-borne pathogens have been reported as an important cause of imported fever, the incidence of Anaplasma phagocytophilum, the causative agent of human granulocytic anaplasmosis (HGA), in travellers is unknown.
We conducted a prospective cohort study to investigate the aetiologies of fever in returning travellers (November 2017-July 2019). Polymerase chain reaction for msp2 gene amplification and indirect immunofluorescence assay for A. phagocitophilum were performed in all returning travellers with undifferentiated non-malarial fever.
Among 141 travellers included, 8 patients were diagnosed with probable or confirmed HGA. The overall incidence rate of HGA was 19.9 cases/1000 person-week of travel. The main destination of travel was Asia, accounting for 62.5% patients with HGA. Co-infections were found in 37.5% of patients with HGA.
Diagnosis of HGA and empirical treatment with doxycycline should be considered in travellers with fever.
Mots-clé
Anaplasma phagocytophilum, Doxycycline, Emerging infections, Fever, Ticks, Travel, Vector-borne diseases, Anaplasma phagocytophilum, doxycycline, emerging infections, fever, ticks, travel, vector-borne diseases
Pubmed
Création de la notice
04/05/2021 8:03
Dernière modification de la notice
30/06/2021 5:34
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