Dynamic contrast-enhanced T2*-weighted MR imaging: a peritumoral brain oedema study.

Détails

ID Serval
serval:BIB_43B4F4A50AA8
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Dynamic contrast-enhanced T2*-weighted MR imaging: a peritumoral brain oedema study.
Périodique
Journal of neuroradiology. Journal de neuroradiologie
Auteur⸱e⸱s
Lehmann P., Vallée J.N., Saliou G., Monet P., Bruniau A., Fichten A., De Marco G.
ISSN
0150-9861 (Print)
ISSN-L
0150-9861
Statut éditorial
Publié
Date de publication
05/2009
Peer-reviewed
Oui
Volume
36
Numéro
2
Pages
88-92
Langue
anglais
Notes
Lehmann, P
Vallee, J-N
Saliou, G
Monet, P
Bruniau, A
Fichten, A
De Marco, G
eng
Comparative Study
France
2008/12/05 09:00
J Neuroradiol. 2009 May;36(2):88-92. doi: 10.1016/j.neurad.2008.10.001. Epub 2008 Dec 2.
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Résumé
Glioma and meningioma are the two most common types of primary brain tumor. The aim of the present study was to analyze, using dynamic susceptibility contrast MR perfusion imaging, the effect of angiogenesis on peritumoral tissue.
In this prospective study, conducted from December 2003 to March 2005, out of 18 patients recruited, 12 were included (six with meningioma, six with glioblastoma). Using rates of maximum signal drop (MSD), we drew regions of interest (ROI) starting near the lesion, and gradually moving outwards to areas of distant edema in axial and sagittal planes at 10, 20 and 30 mm from the tumor. We also drew ROI on the contralateral brain white matter to obtain a normal baseline for comparison (relative MSD; rMSD).
In regions of peritumoral T2 hypersignals, we observed a decrease in rMSD with distance from glioblastoma due to reduced angiogenesis, and an increase in rMSD with distance from meningioma, probably due to a reduced mass effect.
In our study, dynamic susceptibility contrast MR perfusion imaging, using MSD as a parameter, revealed differences between meningioma and glioblastoma peritumoral tissue due to changes in angiogenesis.

Mots-clé
Aged, Brain/pathology, Brain Edema/etiology, Brain Edema/pathology, Brain Mapping/methods, Brain Neoplasms/complications, Brain Neoplasms/diagnosis, Brain Neoplasms/pathology, Diagnostic Imaging, Female, Glioma/complications, Glioma/diagnosis, Glioma/pathology, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging/methods, Male, Meningeal Neoplasms/complications, Meningeal Neoplasms/diagnosis, Meningeal Neoplasms/pathology, Meningioma/complications, Meningioma/diagnosis, Meningioma/pathology, Middle Aged, Prospective Studies, Signal Processing, Computer-Assisted
Pubmed
Création de la notice
20/01/2017 16:30
Dernière modification de la notice
20/08/2019 14:47
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