Prevalence of anaemia in inflammatory bowel disease in Switzerland: a cross-sectional study in patients from private practices and university hospitals.

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Etat: Public
Version: de l'auteur⸱e
ID Serval
serval:BIB_40EE2D5AF539
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Prevalence of anaemia in inflammatory bowel disease in Switzerland: a cross-sectional study in patients from private practices and university hospitals.
Périodique
Journal of Crohn's and Colitis
Auteur⸱e⸱s
Voegtlin M., Vavricka S.R., Schoepfer A.M., Straumann A., Voegtlin J., Rogler G., Ballabeni P., Pittet V., Buser A., Fried M., Beglinger C.
Collaborateur⸱rice⸱s
Swiss IBD Cohort Study
Contributeur⸱rice⸱s
Bauerfeind P., Begré S., Bengoa J., Binek J., Boller D., Borovicka J., Brägger C., Brun P., Burnand B., Camara R., Criblez D., de Saussure P., Degen L., Delarive J., Ehmann T., Engelmann M., El Wafa A., Felley C., Frei A., Frei R., Friedt M., Froehlich F., Gallot-Lavallée S., Gerlach T., Geyer M., Girardin M., Goetze O., Haack H., Hediger S., Hengstler P., Heyland K., Janiak P., Juillerat P., Brondolo VK., Knoblauch C., Kullak-Ublick GA., Manz M., Meier R., Meyenberger C., Michetti P., Mottet C., Müller C., Müllhaupt B., Nicolet T., Nydegger A., Pache I., Piccoli F., Pilz J., Rentsch R., Rey JP., Rogler D., Rihs S., Sagmeister M., Sauter B., Schaub N., Schibli S., Seibold F., Spalinger J., Stadler P., Steuerwald M., Sulz M., Tempia-Caliera M., Thorens£££Joël£££ J. , Vader JP., Von Känel R., Wachter G., Wermuth J., Wiesel P.
ISSN
1876-4479 (Electronic)
ISSN-L
1873-9946
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
4
Numéro
6
Pages
642-648
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish
Résumé
BACKGROUND: Anaemia represents a common complication of inflammatory bowel disease (IBD). Most studies on anaemia in IBD patients have been performed in tertiary referral centres (RC) and data from gastroenterologic practices (GP) are lacking. We investigated the frequency and severity of anaemia in IBD patients from tertiary referral centres and gastroenterologic practices compared to the general population.
METHODS: Data were acquired from patients included in the Swiss IBD Cohort Study. IBD activity was evaluated by CDAI and modified Truelove and Witts severity index (MTWSI). Anaemia was defined as haemoglobin ≤120g/L in women and ≤130g/L in men.
RESULTS: 125 patients from RC (66 with Crohn's disease (CD) and 59 with ulcerative colitis (UC)) and 116 patients from GP (71 CD and 45 UC) were included and compared to 6074 blood donors. Anaemia was found in 21.2% (51/241) of the IBD patients and more frequently in patients from RC as compared to GP and healthy controls (28.8% vs. 12.9% vs. 3.4%; P<0.01). IBD patients from RC suffered more frequently from active disease compared to IBD patients in GP (36% vs. 23%, P=0.032). Supplementation therapy (iron, vitamin B12, folic acid) was performed in 40% of anaemic IBD patients in GP as compared to 43% in RC.
CONCLUSIONS: Anaemia is a common complication in patients with IBD and significantly more prevalent in patients from referral centres as compared to patients from gastroenterologic practices. Physicians treating IBD patients should pay attention to the presence of anaemia and ensure sufficient supplementation therapy.
Mots-clé
Adult, Anemia/blood, Anemia/drug therapy, Anemia, Iron-Deficiency/blood, Anemia, Iron-Deficiency/drug therapy, Colitis, Ulcerative/blood, Colitis, Ulcerative/complications, Crohn Disease/blood, Crohn Disease/complications, Cross-Sectional Studies, Dietary Supplements/statistics & numerical data, Erythrocyte Indices, Female, Ferritins/analysis, Folic Acid/therapeutic use, Hospitals, University/statistics & numerical data, Humans, Inflammatory Bowel Diseases/blood, Inflammatory Bowel Diseases/complications, Iron/therapeutic use, Male, Middle Aged, Prevalence, Private Practice/statistics & numerical data, Prospective Studies, Severity of Illness Index, Sex Distribution, Switzerland/epidemiology, Vitamin B 12/therapeutic use
Pubmed
Web of science
Open Access
Oui
Création de la notice
15/11/2010 8:58
Dernière modification de la notice
20/08/2019 13:40
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