Early and late nosocomial broncho-pulmonary diseases in intensive care. Comparative study of risk factors and of causing bacteria

Détails

ID Serval
serval:BIB_3FAEFC1E3C58
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Early and late nosocomial broncho-pulmonary diseases in intensive care. Comparative study of risk factors and of causing bacteria
Périodique
Presse Med
Auteur⸱e⸱s
Nseir S., Di Pompeo C., Pronnier P., Soubrier S., Onimus T., Saulnier F., Grandbastien B., Roussel-Delvallez M., Mathieu D., Durocher A.
Statut éditorial
Publié
Date de publication
07/2003
Volume
32
Numéro
24
Pages
1111-5
Langue
français
Résumé
OBJECTIVES: Determine the risk factors and germs responsible for early-onset (E) and late-onset (L) nosocomial broncho-pulmonary infections (NBPI), in order to improve preventive strategies and the choice of initial antibiotherapy. METHODS: An observational prospective study conducted in an intensive care unit of 30 beds, from March 1993 to September 1999. The patients presenting with an ENBPI and those with an LNBPI were compared with patients without NBPI using univariate and then multivariate analysis. RESULTS: 517 (14%) of early-onset NBPI were diagnosed, but the majority of NBPI were late-onset (87%). Multiresistant bacteria predominated. The similarity in the germs responsible for the early and late onset forms of NBPI was probably related to the large number of patients transferred from other departments (82%) and having already received antibiotics before their admission to the intensive care unit (49%). Multivariate analysis identified anti-ulcer and long term corticosteroid treatments as common risk factors for early and late onset forms of NBPI, digestive failure, tracheotomy and kidney failure as risk factors for ENBPI and the number of antibiotics used in intensive care and the duration of mechanical ventilation as factors of risk for LNBPI. CONCLUSION: The limited use of antibiotics and anti-ulcer agents could improve the prevention of early and late onset forms of NBPI. The distinction in intensive care between the two forms of NBPI must be emphasized by the notion of prior hospitalization.
Mots-clé
*Intensive Care Units, Anti-Bacterial Agents/therapeutic use, Bronchial Diseases/drug therapy/epidemiology/*microbiology, Cross Infection/drug therapy/epidemiology/*microbiology, Drug Resistance, Multiple, Female, Gram-Negative Bacterial Infections/drug therapy/epidemiology/*microbiology, Gram-Positive Bacterial Infections/drug therapy/epidemiology/*microbiology, Humans, Incidence, Lung Diseases/drug therapy/epidemiology/*microbiology, Male, Middle Aged, Prospective Studies, Risk Factors, Time Factors
Création de la notice
18/07/2019 12:48
Dernière modification de la notice
21/08/2019 5:33
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