Organotypic Models to Study Human Glioblastoma: Studying the Beast in Its Ecosystem.

Détails

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Accès restreint UNIL
Etat: Public
Version: de l'auteur⸱e
Licence: CC BY-NC-ND 4.0
ID Serval
serval:BIB_3EDD5151369D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Organotypic Models to Study Human Glioblastoma: Studying the Beast in Its Ecosystem.
Périodique
iScience
Auteur⸱e⸱s
Pamies D., Zurich M.G., Hartung T.
ISSN
2589-0042 (Electronic)
ISSN-L
2589-0042
Statut éditorial
Publié
Date de publication
23/10/2020
Peer-reviewed
Oui
Volume
23
Numéro
10
Pages
101633
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Résumé
Glioblastoma is a very aggressive primary brain tumor in adults, with very low survival rates and no curative treatments. The high failure rate of drug development for this cancer is linked to the high-cost, time-consuming, and inefficient models used to study the disease. Advances in stem cell and in vitro cultures technologies are promising, however, and here we present the advantages and limitations of available organotypic culture models and discuss their possible applications for studying glioblastoma.
Mots-clé
Bioengineering, Cancer, Clinical Neuroscience, Tissue Engineering
Pubmed
Open Access
Oui
Création de la notice
02/11/2020 12:59
Dernière modification de la notice
23/02/2022 6:36
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