Ultra-fast recovery from right neglect after 'awake surgery' for slow-growing tumor invading the left parietal area

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Etat: Public
Version: de l'auteur⸱e
ID Serval
serval:BIB_3D9A06AF3B6F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Ultra-fast recovery from right neglect after 'awake surgery' for slow-growing tumor invading the left parietal area
Périodique
Neurocase
Auteur⸱e⸱s
Sallard E., Duffau H., Bonnetblanc F.
Statut éditorial
Publié
Date de publication
07/2011
Pages
1-11
Langue
anglais
Résumé
It is now possible to perform resections of slow-growing tumors in awake patients. Using direct electrical stimulation, real-time functional mapping of the brain can be used to prevent the resection of essential areas near the tumor. Simple clinical observations of patients with a resection of slow-growing tumors have demonstrated substantial recovery within a few days of such 'awake surgery'. The aim of this study was to investigate the kinetics of recovery following the resection of slow-growing tumors invading the left parietal area and to focus mainly on its rapidity. Two patients were assessed by standard line bisection tests and compared with eight healthy individuals. Independently of the pure nature of the symptoms, we report that the patients rapidly and substantially recovered from pronounced right neglect. They were tested 48 hours after the surgery and the recovery was significant for both patients after less than 4 hours. Strikingly, for one patient, recovery was ultra fast and substantial in the first practice session within less than 7 minutes: it occurred without verbal feedback and was substantially retained during the following testing session. Its rapidity suggests a process of unmasking redundant networks. With the slow growth of the lesion, the contralesional hemisphere is probably progressively prepared for rapid unmasking of homologue networks. These results have major clinical implications. For patients with an invading left-side tumor, it is now clear that line bisections are required before, during, and after awake surgery to: plan the surgery, control the quality of the resection, and also optimize the rehabilitation of the patient
Mots-clé
Plasticity, Slow-growing tumor, Right hemineglect, Awake surgery.
Web of science
Création de la notice
22/10/2010 10:38
Dernière modification de la notice
20/08/2019 14:34
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