Approach to cytological indeterminate thyroid nodules.

Détails

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Etat: Public
Version: Final published version
Licence: Non spécifiée
ID Serval
serval:BIB_3D6CBC1126E8
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Approach to cytological indeterminate thyroid nodules.
Périodique
Gland surgery
Auteur(s)
Bongiovanni M., Bellevicine C., Troncone G., Sykiotis G.P.
ISSN
2227-684X (Print)
ISSN-L
2227-684X
Statut éditorial
Publié
Date de publication
08/2019
Peer-reviewed
Oui
Volume
8
Numéro
Suppl 2
Pages
S98-S104
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
The indeterminate thyroid nodules diagnosed by fine-needle aspiration cytology (FNAC)represents a problem for both cytopathologists and clinicians. The former sometimes use this diagnostic category as a sort of basket, putting in cases that they do not know exactly how to classify. The latter are faced with a highly variable risk of malignancy and consequently the management remains a challenge. On the histopathological side, the new WHO classification of tumors of the thyroid introduced the concept of tumors with uncertain and low malignant potential, and the concept of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP), whose prognosis and management are still to be completely elucidated. While the risk of malignancy of the indeterminate diagnostic category has decreased due to the re-classification of certain types of papillary thyroid carcinomas of the follicular variant into a low malignant potential form (the NIFTP), cases diagnosed cytologically as indeterminate will probably increase in the future to avoid false positive diagnosis. Thus, the indeterminate thyroid diagnostic category still remains a challenge, both at the diagnostic level and for its management. The new version of the Bethesda system for reporting thyroid cytopathology suggests managing these patients with a repeat FNA, diagnostic lobectomy and/or molecular testing.
Mots-clé
Atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS), follicular neoplasm or suspicious for a follicular neoplasm (FN/SFN), indeterminate diagnosis, the Bethesda system, thyroid fine-needle aspiration cytology (thyroid FNAC)
Pubmed
Web of science
Open Access
Oui
Création de la notice
09/04/2019 14:01
Dernière modification de la notice
04/09/2019 7:08
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