The emergence of new genes on the young therian X.

Détails

ID Serval
serval:BIB_3CE20BAB7471
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
The emergence of new genes on the young therian X.
Périodique
Trends in Genetics
Auteur(s)
Potrzebowski L., Vinckenbosch N., Kaessmann H.
ISSN
0168-9525[print], 0168-9525[linking]
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
26
Numéro
1
Pages
1-4
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish
Résumé
Recent studies have revealed that our sex chromosomes differentiated relatively recently from ancestral autosomes in the common ancestor of placental and marsupial mammals (therians). Here, we show that the therian X started to accumulate new retroduplicate genes with overall sex-biased expression upon therian sex chromosome differentiation. This process reached its peak within the first approximately 90 million years of sex chromosome evolution and then leveled off. Taken together, our observations suggest that the major sex-related functional remodeling of the X was completed relatively soon after the origination of therian sex chromosomes.
Mots-clé
Aging, Animals, Evolution, Molecular, Gene Expression Regulation, Humans, Mammals/genetics, X Chromosome
Pubmed
Web of science
Création de la notice
27/01/2010 19:12
Dernière modification de la notice
20/08/2019 14:33
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