Hereditary thrombophilia and venous thromboembolism: critical evaluation of the clinical implications of screening

Détails

ID Serval
serval:BIB_3CC34FD5C6E9
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Hereditary thrombophilia and venous thromboembolism: critical evaluation of the clinical implications of screening
Périodique
European Journal of Vascular and Endovascular Surgery
Auteur(s)
Mazzolai  L., Duchosal  M. A.
ISSN
1078-5884 (Print)
Statut éditorial
Publié
Date de publication
10/2007
Volume
34
Numéro
4
Pages
483-488
Langue
anglais
Notes
Journal Article Review --- Old month value: Oct
Résumé
Venous thromboembolism is a complex disease resulting from the interactions of several risk factors from diverse origins: genetic, environmental and behavioral. Numerous studies have evidenced an association between genetic thrombophilia defects and venous thromboembolism. However, the clinical relevance of genetic thrombophilia to recurrent venous thromboembolism is not clear and the risks of long-term anticoagulant treatment usually outweigh any benefits of hereditary thrombophilia screening. Therefore, in everyday clinical practice (outside of research protocols) hereditary thrombophilia screening should be performed only in cases where such testing is likely to influence patient management.
Mots-clé
Anticoagulants/therapeutic use Genetic Predisposition to Disease *Genetic Screening Humans Recurrence Risk Assessment Thromboembolism/*etiology/prevention & control Thrombophilia/*genetics Venous Thrombosis/*etiology/prevention & control
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/01/2008 15:24
Dernière modification de la notice
20/08/2019 13:32
Données d'usage