A Selective Culture Medium for Screening Ceftazidime-Avibactam Resistance in Enterobacterales and Pseudomonas aeruginosa.

Détails

ID Serval
serval:BIB_3A49BFA7551F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
A Selective Culture Medium for Screening Ceftazidime-Avibactam Resistance in Enterobacterales and Pseudomonas aeruginosa.
Périodique
Journal of clinical microbiology
Auteur⸱e⸱s
Sadek M., Poirel L., Tinguely C., Nordmann P.
ISSN
1098-660X (Electronic)
ISSN-L
0095-1137
Statut éditorial
Publié
Date de publication
24/08/2020
Peer-reviewed
Oui
Volume
58
Numéro
9
Pages
e00965-20
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Résumé
The SuperCAZ/AVI medium was developed for screening ceftazidime-avibactam (CZA) resistance among Gram-negative bacteria (Enterobacterales and Pseudomonas aeruginosa). It was evaluated using 50 CZA-susceptible and 42 CZA-resistant Gram-negative isolates. Its sensitivity and specificity of detection were 100%. Excellent performance of the medium was also observed by testing spiked stools, with the lower limit of detection ranging from 10 <sup>1</sup> to 10 <sup>2</sup> CFU/ml. This screening medium provides the opportunity to detect CZA-resistant isolates regardless of their resistance mechanisms.
Mots-clé
Anti-Bacterial Agents/pharmacology, Anti-Bacterial Agents/therapeutic use, Azabicyclo Compounds, Ceftazidime/pharmacology, Drug Combinations, Drug Resistance, Multiple, Bacterial, Humans, Microbial Sensitivity Tests, Pseudomonas aeruginosa, Enterobacterales, avibactam, ceftazidime, screening
Pubmed
Web of science
Open Access
Oui
Création de la notice
03/07/2020 17:42
Dernière modification de la notice
06/04/2024 6:24
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