Effect of incident light wavelength and corneal edema on light scattering and penetration: laboratory study of human corneas.

Détails

ID Serval
serval:BIB_3A27BE0B70CB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Effect of incident light wavelength and corneal edema on light scattering and penetration: laboratory study of human corneas.
Périodique
Journal of Refractive Surgery (thorofare, N.j. : 1995)
Auteur⸱e⸱s
Peyrot D.A., Aptel F., Crotti C., Deloison F., Lemaire S., Marciano T., Bancelin S., Alahyane F., Kowalczuk L., Savoldelli M., Legeais J.M., Plamann K.
ISSN
1081-597X (Print)
ISSN-L
1081-597X
Statut éditorial
Publié
Date de publication
10/2010
Peer-reviewed
Oui
Volume
26
Numéro
10
Pages
786-795
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
PURPOSE: The outcome of ultrashort pulse laser surgery of the cornea is strongly influenced by the light scattering properties of the tissue, for which little data are available. The purpose of the present study is to provide quantitative values for light scattering and its relation to the degree of edema.
METHODS: An experimental optical measuring setup based on confocal geometry was used to measure the unscattered and scattered fractions of light transmitted by eye bank corneas presenting various degrees of edema. From these measurements, the effective light penetration depth in the cornea was calculated as a function of wavelength.
RESULTS: Corneal transparency depends on the pathological state of the cornea and on wavelength. It may be predicted as a function of corneal thickness, ie, the degree of edema. In healthy and edematous cornea, the percentage of scattered light decreases with increasing wavelength. The total penetration depths at the wavelengths of ~1050 nm (which is used in typical clinical systems) and 1650 nm (which is recommended for future devices) are comparable; however, the former is limited by scattering, which degrades the laser beam quality, whereas the latter is only limited by optical absorption, which may be compensated for.
CONCLUSIONS: The use of longer wavelengths should help improve the surgical outcome in ultrashort pulse laser surgery of the cornea when working on pathological tissue. A wavelength of approximately 1650 nm appears to be a good compromise, as it allows for reduced light scattering while keeping optical absorption reasonably low.
Mots-clé
Cornea/radiation effects, Corneal Edema/etiology, Humans, Light, Scattering, Radiation
Pubmed
Web of science
Création de la notice
01/03/2016 15:14
Dernière modification de la notice
20/08/2019 13:29
Données d'usage