Tamponade efficiency of perfluorohexyloctane and silicone oil solutions in a model eye chamber.

Détails

ID Serval
serval:BIB_38A51071AF70
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Tamponade efficiency of perfluorohexyloctane and silicone oil solutions in a model eye chamber.
Périodique
The British journal of ophthalmology
Auteur⸱e⸱s
Wetterqvist C., Wong D., Williams R., Stappler T., Herbert E., Freeburn S.
ISSN
0007-1161 (Print)
ISSN-L
0007-1161
Statut éditorial
Publié
Date de publication
05/2004
Peer-reviewed
Oui
Volume
88
Numéro
5
Pages
692-696
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
As no single tamponade agent yet fulfils all the requirements of a long term inferior tamponade, attempts have been made to mix tamponade materials. This study investigated perfluorohexyloctane (F(6)H(8)) and silicone oil solutions designed to take advantage of the high specific gravity and interfacial tension of the F(6)H(8) and the high viscosity of silicone oil.
Solutions of three different densities were examined (1.01, 1.03 and 1.06 g/cm(3)) inside transparent chambers made of surface modified poly(methylmethacrylate) (PMMA).
Compared to F(6)H(8), the solutions had poorer contact with hydrophilic surface of the chambers. The higher the specific gravity of the solution, the better was the contact. The solution with a specific gravity 1.01 g/cm(3) is probably of no use clinically.
The model eye chamber made of surface modified PMMA is an efficient way of screening and choosing solutions with promising physical properties. Solutions of silicone oil with F(6)H(8) in other proportions or with other semifluorinated alkanes may be of interest.
Mots-clé
Chemical Phenomena, Chemistry, Physical, Eye/anatomy & histology, Fluorocarbons/chemistry, Humans, Models, Anatomic, Polymethyl Methacrylate, Pressure, Retinal Detachment/therapy, Silicone Oils/chemistry, Specific Gravity, Surface Properties, Viscosity
Pubmed
Web of science
Création de la notice
31/08/2018 9:06
Dernière modification de la notice
20/08/2019 13:28
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