SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling.

Détails

ID Serval
serval:BIB_35C2EFFA82F1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling.
Périodique
Electrophoresis
Auteur⸱e⸱s
Guex N., Peitsch M.C.
ISSN
0173-0835 (Print)
ISSN-L
0173-0835
Statut éditorial
Publié
Date de publication
12/1997
Peer-reviewed
Oui
Volume
18
Numéro
15
Pages
2714-2723
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Comparative protein modeling is increasingly gaining interest since it is of great assistance during the rational design of mutagenesis experiments. The availability of this method, and the resulting models, has however been restricted by the availability of expensive computer hardware and software. To overcome these limitations, we have developed an environment for comparative protein modeling that consists of SWISS-MODEL, a server for automated comparative protein modeling and of the SWISS-PdbViewer, a sequence to structure workbench. The Swiss-PdbViewer not only acts as a client for SWISS-MODEL, but also provides a large selection of structure analysis and display tools. In addition, we provide the SWISS-MODEL Repository, a database containing more than 3500 automatically generated protein models. By making such tools freely available to the scientific community, we hope to increase the use of protein structures and models in the process of experiment design.
Mots-clé
Amino Acid Sequence, Automation, Databases, Factual, Models, Molecular, Molecular Sequence Data, Reproducibility of Results, Sequence Homology, Amino Acid
Pubmed
Web of science
Création de la notice
29/01/2021 14:54
Dernière modification de la notice
30/01/2021 6:26
Données d'usage