Antiplatelets in stroke prevention: the MATCH trial. Some answers, many questions and countless perspectives.

Détails

ID Serval
serval:BIB_35314
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Antiplatelets in stroke prevention: the MATCH trial. Some answers, many questions and countless perspectives.
Périodique
Cerebrovascular Diseases (basel, Switzerland)
Auteur(s)
Bezerra D.C., Bogousslavsky J.
ISSN
1015-9770 (Print)
ISSN-L
1015-9770
Statut éditorial
Publié
Date de publication
2005
Volume
20 Suppl 2
Numéro
Suppl. 2
Pages
109-118
Langue
anglais
Notes
Publication types: Journal Article ; Multicenter Study ; Randomized Controlled Trial
Publication Status: ppublish
Résumé
Antiplatelet drugs have an established efficacy in the secondary prevention of ischemic stroke. The recent results of the CAPRIE, CURE, and CREDO studies formed the rationale for the MATCH, designed to test whether the association of clopidogrel and aspirin was better than clopidogrel alone for the prevention of vascular events among high-risk ischemic cerebrovascular patients. Although the benefits were outweighed for a higher bleeding risk in the combination group, this study will provide important insight for upcoming trials in other to determine what populations might mostly benefit from these drugs for the secondary prevention of stroke in the future.
Mots-clé
Age Factors, Aged, Aspirin/adverse effects, Aspirin/therapeutic use, Cerebrovascular Disorders/complications, Drug Therapy, Combination, Female, Hemorrhage/chemically induced, Humans, Ischemic Attack, Transient/complications, Male, Middle Aged, Platelet Aggregation Inhibitors/adverse effects, Platelet Aggregation Inhibitors/therapeutic use, Recurrence/prevention & control, Risk Factors, Stroke/epidemiology, Stroke/prevention & control, Ticlopidine/adverse effects, Ticlopidine/analogs & derivatives, Treatment Outcome
Pubmed
Création de la notice
19/11/2007 13:33
Dernière modification de la notice
20/08/2019 14:22
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