Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee.

Détails

ID Serval
serval:BIB_34F5DCB86E0F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee.
Périodique
Nucleic Acids Research
Auteur⸱e⸱s
Armougom F., Moretti S., Poirot O., Audic S., Dumas P., Schaeli B., Keduas V., Notredame C.
ISSN
1362-4962[electronic]
Statut éditorial
Publié
Date de publication
07/2006
Volume
34
Numéro
Web Server issue
Pages
W604-W608
Langue
anglais
Notes
Publication types: Journal Article
Résumé
Expresso is a multiple sequence alignment server that aligns sequences using structural information. The user only needs to provide sequences. The server runs BLAST to identify close homologues of the sequences within the PDB database. These PDB structures are used as templates to guide the alignment of the original sequences using structure-based sequence alignment methods like SAP or Fugue. The final result is a multiple sequence alignment of the original sequences based on the structural information of the templates. An advanced mode makes it possible to either upload private structures or specify which PDB templates should be used to model each sequence. Providing the suitable structural information is available, Expresso delivers sequence alignments with accuracy comparable with structure-based alignments. The server is available on http://www.tcoffee.org/.
Mots-clé
Databases, Protein, Internet, Protein Conformation, Sequence Alignment/methods, Software, User-Computer Interface
Pubmed
Open Access
Oui
Création de la notice
19/11/2007 10:07
Dernière modification de la notice
20/08/2019 13:22
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