Comparison of a conventional HIV 1/2 line immunoassay with a rapid confirmatory HIV 1/2 assay.

Détails

ID Serval
serval:BIB_33FBB8CA1682
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Comparison of a conventional HIV 1/2 line immunoassay with a rapid confirmatory HIV 1/2 assay.
Périodique
Journal of Virological Methods
Auteur(s)
Tinguely C., Schild-Spycher T., Bahador Z., Gowland P., Stolz M., Niederhauser C.
ISSN
1879-0984 (Electronic)
ISSN-L
0166-0934
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
206
Pages
1-4
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish
Résumé
The performance of the rapid confirmatory HIV 1/2 assay Geenius was compared with the conventional HIV 1/2 line immunoblot (INNO-LIA HIV I/II Score). One hundred HIV 1/2 confirmed positive samples from donors and patients and 136 negative screening samples from blood donors were evaluated with both assays. A 20 member performance panel consisting of different HIV 1 and 2 subtypes was also analysed. Ninety-nine of the confirmed HIV positive samples were positive with both assays. One sample was positive with the INNO-LIA HIV I/II Score but indeterminate with the Geenius HIV 1/2. From 136 negative blood donor samples (negative with a combo HIV assay and a highly sensitive ID-NAT), 125 were concordant negative. Six and five samples were incorrectly indeterminate with the INNO-LIA HIV I/II Score and the Geenius HIV 1/2, respectively. One sample was weak positive with the INNO-LIA HIV I/II Score but negative with the Geenius HIV 1/2. The 20 member performance showed equivalent results with both assays. The rapid assay showed a comparable sensitivity and specificity for confirmation for positive and negative HIV donor and patient samples as well for a 20 member performance panel.
Pubmed
Web of science
Création de la notice
09/11/2014 16:56
Dernière modification de la notice
20/08/2019 14:20
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