Effect of embryo culture media on birthweight and length in singleton term infants after IVF-ICSI.

Détails

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Etat: Public
Version: Final published version
ID Serval
serval:BIB_333B02D0FD19
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Effect of embryo culture media on birthweight and length in singleton term infants after IVF-ICSI.
Périodique
Swiss Medical Weekly
Auteur(s)
Wunder D., Ballabeni P., Roth-Kleiner M., Primi M.P., Senn A., Chanson A., Germond M., Leyvraz C.
ISSN
1424-3997 (Electronic)
ISSN-L
0036-7672
Statut éditorial
Publié
Date de publication
2014
Volume
144
Pages
w14038
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: epublish
Résumé
QUESTIONS UNDER STUDY: To investigate if two distinct, commercially available embryo culture media have a different effect on birthweight and length of singleton term infants conceived after IVF-ICSI.
METHODS: University hospital based cohort study. Between 1 January 2000 and 31 December 2004, patients conceiving through IVF-ICSI at the University Hospital, Lausanne have been allocated to two distinct embryo culture media. Only term singleton pregnancies were analysed (n = 525). Data analysis was performed according to two commercially available culture media: Vitrolife (n = 352) versus Cook (n = 173). Analysis was performed through linear regression adjusted for confounders. Media were considered equivalent if the 95% confidence interval lay between -150 g/+150 g.
RESULTS: Length, gestational age and distribution of birthweight percentiles did not differ between groups (for both genders). Analysis of the whole cohort, adjusted for a subset of confounders, resulted in a statistically not different mean birthweight between the two groups (Vitrolife +37 g vs Cook, 95%CI: -46 g to 119 g) suggesting equivalence. Adjustment for an enlarged number of confounders in a subsample of patients (n = 258) also revealed no relevant mean birthweight difference of +71 g (95%CI: -45 g to 187 g) in favour of Vitrolife; however, lacking power to prove equivalence.
CONCLUSIONS: Our data suggest that significant differences in birthweight due to these two distinct, commercially available embryo culture media are unlikely.
Pubmed
Web of science
Open Access
Oui
Création de la notice
13/11/2014 18:28
Dernière modification de la notice
20/08/2019 13:19
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