Immune senescence and vaccination in the elderly.

Détails

ID Serval
serval:BIB_332826233AD9
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Immune senescence and vaccination in the elderly.
Périodique
Current Topics In Medicinal Chemistry
Auteur(s)
Lang P.O., Govind S., Bokum A.T., Kenny N., Matas E., Pitts D., Aspinall R.
ISSN
1873-4294 (Electronic)
ISSN-L
1568-0266
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
13
Numéro
20
Pages
2541-2550
Langue
anglais
Notes
Publication types: Journal Article ; Review Publication Status: ppublish
Résumé
Vaccines are powerful public health tools that have been of tremendous benefit in protecting vulnerable populations worldwide from many pathogens. However, vaccine- preventable diseases still remain a considerable burden and this is particularly true among aging and aged populations in industrialized countries. The predicted demographic shift in the population landscape towards an ever-increasing aging population and the evidence suggesting that older individuals mount less-than optimal immune response to vaccination have raised the question of improving vaccine responses in older individuals. This review presents recent progress in the understanding at the cellular and molecular levels of age related immune decline and strategies to translate current knowledge into the development of immunization strategies to promote healthy aging, keeping older members of our society autonomous and independent.
Mots-clé
Aged, Aging/immunology, Humans, Public Health, Vaccination, Vaccines/immunology
Pubmed
Web of science
Création de la notice
15/04/2015 9:03
Dernière modification de la notice
20/08/2019 13:19
Données d'usage