Insulin: a model system for nanomedicine?

Détails

ID Serval
serval:BIB_32F431DDC711
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Insulin: a model system for nanomedicine?
Périodique
Nanomedicine
Auteur(s)
Koch M., Schmid F.F., Zoete V., Meuwly M.
ISSN
1748-6963 (Electronic)
ISSN-L
1743-5889
Statut éditorial
Publié
Date de publication
10/2006
Peer-reviewed
Oui
Volume
1
Numéro
3
Pages
373-378
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Résumé
One of the predominant aims of insulin therapy for diabetes is to appropriately mimic physiological insulin secretion levels and their correlation with glucose concentration in healthy individuals. This report outlines current methods and their limitations in glycemic control and their possible relationship to insufficient knowledge about the structure and dynamics of the insulin hormone itself. Based on recent experimental and computational work, a possible approach to less-invasive insulin administration is sketched.

Mots-clé
Animals, Computer Simulation, Dimerization, Humans, Insulin/chemistry, Insulin/pharmacokinetics, Insulin/therapeutic use, Models, Molecular, Nanomedicine/methods, Nanomedicine/trends, Nanoparticles/chemistry
Pubmed
Web of science
Création de la notice
05/02/2018 14:59
Dernière modification de la notice
21/08/2019 5:37
Données d'usage