IGF-1, IGFBP-3, and nutritional factors in young black and white men: the CARDIA Male Hormone Study.

Détails

ID Serval
serval:BIB_324524DC9CF7
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
IGF-1, IGFBP-3, and nutritional factors in young black and white men: the CARDIA Male Hormone Study.
Périodique
Nutrition and cancer
Auteur(s)
Colangelo L.A., Chiu B.C., Liu K., Kopp P.A., Gann P.H., Gapstur S.M.
ISSN
0163-5581 (Print)
ISSN-L
0163-5581
Statut éditorial
Publié
Date de publication
2005
Peer-reviewed
Oui
Volume
53
Numéro
1
Pages
57-64
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, N.I.H., Extramural
Publication Status: ppublish
Résumé
Nutritional factors might play a role in regulating serum levels of insulin-like growth factors (IGFs), which are associated with some cancers. We examined the associations of nutritional factors with IGF-1 and IGF binding protein-3 (IGFBP-3). Serum IGF-1 and IGFBP-3 levels and dietary intake were measured in 459 black and 682 white male subjects of the Coronary Artery Risk Development in Young Adults study at the Year 7 (1992-1993) exam. Analysis of covariance and multivariable linear regression were used to assess associations of IGFs with dietary factors by race. IGF-1 was positively associated with magnesium in both black and white men (P = 0.008 and 0.05, respectively). Calcium was positively significantly related to IGF-1 in black men (P = 0.04) and marginally so in white men (P = 0.09). In black men, IGFBP-3 was positively associated with magnesium (P = 0.02), and one serving of milk per day was associated with an 8.23-ng/ml higher IGF-1 concentration (P = 0.05). Tests for interaction, however, revealed no differences between blacks and whites in the associations of nutrients with IGF-1 or IGFBP-3. In conclusion, the associations of dietary factors with serum IGF-1 and IGFBP-3 observed in our study corroborate those from other studies and generally do not differ between black and white men.
Mots-clé
Adult, African Continental Ancestry Group, Analysis of Variance, Calcium/blood, Cohort Studies, European Continental Ancestry Group, Humans, Insulin-Like Growth Factor Binding Protein 3/blood, Insulin-Like Growth Factor I/analysis, Linear Models, Longitudinal Studies, Magnesium/blood, Male
Pubmed
Web of science
Création de la notice
30/12/2020 14:30
Dernière modification de la notice
31/12/2020 6:26
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