Enzymatic but not compensated Jaffe methods reach the desirable specifications of NKDEP at normal levels of creatinine. Results of the French multicentric evaluation

Détails

ID Serval
serval:BIB_318CF2412E12
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Enzymatic but not compensated Jaffe methods reach the desirable specifications of NKDEP at normal levels of creatinine. Results of the French multicentric evaluation
Périodique
Clin Chim Acta
Auteur(s)
Boutten A., Bargnoux A. S., Carlier M. C., Delanaye P., Rozet E., Delatour V., Cavalier E., Hanser A. M., Froissart M., Cristol J. P., Pieroni L., Societe Francaise de Biologie Clinique
ISSN
1873-3492 (Electronic))
ISSN-L
0009-8981
Statut éditorial
Publié
Date de publication
2013
Volume
419
Pages
132-5
Langue
anglais
Notes
Boutten, Anne
Bargnoux, Anne-Sophie
Carlier, Marie-Christine
Delanaye, Pierre
Rozet, Eric
Delatour, Vincent
Cavalier, Etienne
Hanser, Anne-Marie
Froissart, Marc
Cristol, Jean-Paul
Pieroni, Laurence
eng
Evaluation Studies
Multicenter Study
Netherlands
2013/02/19 06:00
Clin Chim Acta. 2013 Apr 18;419:132-5. doi: 10.1016/j.cca.2013.01.021. Epub 2013 Feb 13.
Résumé
The French Society of Clinical Biochemistry conducted this study to compare the accuracy and performances of the best creatinine enzymatic assays and the compensated Jaffe methods from the same manufacturers. Creatinine was measured in 3 serum pools with creatinine levels of 35.9+/-0.9 mumol/L, 74.4+/-1.4 mumol/L, and 97.9+/-1.7 mumol/L (IDMS determination). The performances of the assays (total error that includes the contribution of bias and imprecision) were evaluated using Monte-Carlo simulations and compared against desirable NKDEP criteria. The enzymatic assays always fell within the desirable total Error of 7.6%. By contrast, this requirement was never obtained for the compensated Jaffe methods at the critical level of 74.4+/-1.4 mumol/L. Only the compensated Jaffe creatinine on Olympus analyzer reached this specification at 35.9+/-0.9 and 97.9+/-1.7 mumol/L levels. This study demonstrates that, despite substantial improvement regarding traceability to the IDMS reference method and precision, compensated Jaffe creatinine methods, by contrast to enzymatic ones, do not reach the desirable specifications of NKDEP at normal levels of creatinine.
Mots-clé
Creatinine/*blood/metabolism, *Enzyme Assays, France, Humans, Kidney Diseases/blood/*diagnosis, National Health Programs, Sensitivity and Specificity
Pubmed
Création de la notice
03/03/2016 17:49
Dernière modification de la notice
21/08/2019 6:35
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