Le pic de masse osseuse: realites et incertitudes. [Peak bone mass: facts and uncertainties]

Détails

ID Serval
serval:BIB_316133F5CE88
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Le pic de masse osseuse: realites et incertitudes. [Peak bone mass: facts and uncertainties]
Périodique
Archives de Pediatrie
Auteur(s)
Bonjour  J. P., Theintz  G., Law  F., Slosman  D., Rizzoli  R.
ISSN
0929-693X (Print)
Statut éditorial
Publié
Date de publication
05/1995
Volume
2
Numéro
5
Pages
460-8
Notes
English Abstract
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: May
Résumé
Peak bone mass, which can be defined as the amount of bony tissue present at the end of the skeletal maturation, is an important determinant of osteoporotic fracture risk in adulthood. The techniques of single or dual energy absorptiometry measure the so-called "areal" or "surface" bone mineral density (BMD), a variable which has been shown to be directly related to bone strength. During puberty the gender difference in bone mass becomes expressed. This difference appears to be essentially due to a more prolonged bone maturation period in males than in females, with a larger increase in bone size and cortical thickness, as there is no significant sex difference in the volumetric trabecular density at the end of pubertal maturation. At the beginning of the 3rd decade, there is a large variability in the normal values of areal BMD in axial and appendicular skeleton. This large variance, which is observed at sites particularly susceptible to osteoporotic fractures in adulthood, such as lumbar spine and femoral neck, is barely reduced after correction for statural height, and does not appear to substantially increase during adult life. It is generally accepted that peak bone mass at any skeletal site is attained in both sexes during the mid-thirties. However, recent studies indicate that in healthy caucasian females, bone mass accumulation can virtually be completed before the end of the second decade, for both lumbar spine and femoral neck. Several variables are supposed to influence bone mass accumulation during growth: heredity, sex, diet components, endocrine factors, mechanical forces, and exposure to risk factors.(ABSTRACT TRUNCATED AT 250 WORDS)
Mots-clé
Adolescent Adult Age Factors Aged *Bone Density/genetics/physiology Female Humans Male Middle Aged Puberty/physiology Sex Factors
Pubmed
Web of science
Création de la notice
25/01/2008 10:30
Dernière modification de la notice
20/08/2019 13:16
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