Evolution of vitellogenin genes: comparative analysis of the nucleotide sequences downstream of the transcription initiation site of four Xenopus laevis and one chicken gene.

Détails

ID Serval
serval:BIB_2EB65F6DD4C7
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Evolution of vitellogenin genes: comparative analysis of the nucleotide sequences downstream of the transcription initiation site of four Xenopus laevis and one chicken gene.
Périodique
Nucleic Acids Research
Auteur⸱e⸱s
Germond J.E., Walker P., ten Heggeler B., Brown-Luedi M., de Bony E., Wahli W.
ISSN
0305-1048[print], 0305-1048[linking]
Statut éditorial
Publié
Date de publication
11/1984
Volume
12
Numéro
22
Pages
8595-8609
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Electron microscopic analysis of heteroduplexes between the most distantly related Xenopus vitellogenin genes (A genes X B genes) has revealed the distribution of homologous regions that have been preferentially conserved after the duplication events that gave rise to the multigene family in Xenopus laevis. DNA sequence analysis was limited to the region downstream of the transcription initiation site of the Xenopus genes A1, B1 and B2 and a comparison with the Xenopus A2 and the major chicken vitellogenin gene is presented. Within the coding regions of the first three exons, nucleotide substitutions resulting in amino acid changes accumulate at a rate similar to that observed in globin genes. This suggests that the duplication event which led to the formation of the A and B ancestral genes in Xenopus laevis occurred about 150 million years ago. Homologous exons of the A1-A2 and B1-B2 gene pairs, which formed about 30 million years ago, show a quite similar sequence divergence. In contrast, A1-A2 homologous introns seem to have evolved much faster than their B1-B2 counterparts.
Mots-clé
Amino Acid Sequence, Animals, Base Sequence, Chickens, Cloning, Molecular, Evolution, Genes, Lipoproteins/genetics, Microscopy, Electron, Species Specificity, Transcription, Genetic, Vitellogenins/genetics, Xenopus
Pubmed
Web of science
Création de la notice
24/01/2008 16:04
Dernière modification de la notice
20/08/2019 13:13
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