Renal effects of converting enzyme inhibition

Détails

ID Serval
serval:BIB_2C177BD7E41C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Renal effects of converting enzyme inhibition
Périodique
Journal of Cardiovascular Pharmacology
Auteur⸱e⸱s
Brunner  H. R., Waeber  B., Nussberger  J.
ISSN
0160-2446 (Print)
Statut éditorial
Publié
Date de publication
1987
Volume
9 Suppl 3
Pages
S6-14
Notes
Journal Article
Review
Résumé
Angiotensin-converting enzyme inhibition, by preventing the generation of angiotensin II, has some pronounced effects on renal function. Its actions occur at the vascular, the glomerular, the juxtaglomerular, and also at the tubular medullary level. In clinical medicine, depending on the circumstances of the patients under treatment, converting enzyme inhibitors can interfere with renal hemodynamics and glomerular filtration, with solute excretion by the kidney and other variables of normal renal function. In most circumstances, the effects of converting enzyme inhibition on the kidney are rather beneficial to the patient. However, under some extreme conditions, they may become potentially hazardous. A basic understanding of the physiology of the renin-angiotensin system and of its actions on the kidney makes it possible to understand the impact of the converting enzyme inhibitors, to avoid most of the unwanted effects and to ensure greatest benefit to the patient.
Mots-clé
*Angiotensin-Converting Enzyme Inhibitors Humans Kidney/*drug effects Renal Circulation/drug effects
Pubmed
Web of science
Création de la notice
05/03/2008 16:40
Dernière modification de la notice
20/08/2019 13:11
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