Bronchial neuroendocrine (carcinoid) tumor causing unilateral left-sided carcinoid heart disease

Détails

ID Serval
serval:BIB_2A8EBF59AD4A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Bronchial neuroendocrine (carcinoid) tumor causing unilateral left-sided carcinoid heart disease
Périodique
Klinische Wochenschrift
Auteur(s)
Greminger  P., Hess  O. M., Muller  A. E., von Segesser  L., Schneider  J., Sutsch  G., Siegenthaler  W., Heitz  P. U.
ISSN
0023-2173
Statut éditorial
Publié
Date de publication
02/1991
Volume
69
Numéro
3
Pages
128-33
Notes
Case Reports
Journal Article --- Old month value: Feb 6
Résumé
A female patient suffering from a bronchial neuroendocrine tumor with unilateral left-sided carcinoid heart disease is reported. Repeated x-ray films of the chest showed a slowly growing lung tumor in the left lower lobe. The patient refused any diagnostic or therapeutic procedure to define the type of the tumor. During the follow-up of 24 years she developed severe mitral and moderate to severe aortic insufficiency, both invasively quantified by thermodilution techniques. During surgery for double valve replacement the patient died from left ventricular heart failure. Necropsy revealed the typical pattern of a bronchial neuroendocrine tumor without metastases. Examination of the heart disclosed the characteristic deposits of fibrous tissue on the cusps of both the mitral and the aortic valves whereas the right heart showed no abnormalities. Review of the literature suggests the unilateral left-sided carcinoid heart disease to be a very rare finding, its pathogenesis remains to be elucidated.
Mots-clé
Aged Bronchial Neoplasms/*complications/pathology/radiography Carcinoid Heart Disease/*etiology/pathology Carcinoid Tumor/*complications/pathology/radiography Female Humans Tomography, X-Ray Computed
Pubmed
Web of science
Création de la notice
14/02/2008 14:16
Dernière modification de la notice
20/08/2019 13:10
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