Pharmacologic Treatment of Eosinophilic Esophagitis: An Update.

Détails

ID Serval
serval:BIB_2915A21A672A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Pharmacologic Treatment of Eosinophilic Esophagitis: An Update.
Périodique
Gastrointestinal endoscopy clinics of North America
Auteur⸱e⸱s
Schoepfer A.M., Straumann A., Safroneeva E.
ISSN
1558-1950 (Electronic)
ISSN-L
1052-5157
Statut éditorial
Publié
Date de publication
01/2018
Peer-reviewed
Oui
Volume
28
Numéro
1
Pages
77-88
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Eosinophilic esophagitis (EoE) is defined as a chronic, immune-medicated or antigen-mediated, esophageal disease, characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophil-predominant inflammation. Food allergens are identified in most patients. Treatment strategies include elimination diets, drugs, and esophageal dilation. This article focuses on pharmacologic treatment. Currently, there is no pharmacologic treatment that has been approved by regulatory authorities. Established pharmacologic options to treat EoE include proton pump inhibitors and swallowed topical steroids. Several biologic therapies are currently under evaluation and some of them have shown promising results in improving biologic endpoints and patient-reported outcomes.
Mots-clé
Administration, Topical, Anti-Allergic Agents/therapeutic use, Anti-Inflammatory Agents/administration & dosage, Anti-Inflammatory Agents/therapeutic use, Antibodies, Monoclonal/therapeutic use, Budesonide/therapeutic use, Eosinophilic Esophagitis/drug therapy, Eosinophilic Esophagitis/etiology, Fluticasone/therapeutic use, Histamine Antagonists/therapeutic use, Humans, Pregnenediones/therapeutic use, Proton Pump Inhibitors/therapeutic use, Biologic therapy, Budesonide, Eosinophilic esophagitis, Fluticasone, Pharmacologic treatment, Proton pump inhibitors
Pubmed
Création de la notice
22/11/2017 9:48
Dernière modification de la notice
20/08/2019 14:08
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