Dosimetric comparison of different treatment modalities for stereotactic radiosurgery of meningioma.

Détails

ID Serval
serval:BIB_28A8C626A590
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Dosimetric comparison of different treatment modalities for stereotactic radiosurgery of meningioma.
Périodique
Acta Neurochirurgica
Auteur⸱e⸱s
Kaul D., Badakhshi H., Gevaert T., Pasemann D., Budach V., Tulaesca C., Gruen A., Prasad V., Levivier M., Kufeld M.
ISSN
0942-0940 (Electronic)
ISSN-L
0001-6268
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
157
Numéro
4
Pages
559-564
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish
Résumé
BACKGROUND: The objective of this study was to compare the three most prominent systems for stereotactic radiosurgery in terms of dosimetric characteristics: the Cyberknife system, the Gamma Knife Perfexion and the Novalis system.
METHODS: Ten patients treated for recurrent grade I meningioma after surgery using the Cyberknife system were identified; the Cyberknife contours were exported and comparative treatment plans were generated for the Novalis system and Gamma Knife Perfexion. Dosimetric values were compared with respect to coverage, conformity index (CI), gradient index (GI) and beam-on time (BOT).
RESULTS: All three systems showed comparable results in terms of coverage. The Gamma Knife and the Cyberknife system showed significantly higher levels of conformity than the Novalis system (Cyberknife vs Novalis, p = 0.002; Gamma Knife vs Novalis, p = 0.002). The Gamma Knife showed significantly steeper gradients compared with the Novalis and the Cyberknife system (Gamma Knife vs Novalis, p = 0.014; Gamma Knife vs Cyberknife, p = 0.002) and significantly longer beam-on times than the other two systems (BOT = 66 ± 21.3 min, Gamma Knife vs Novalis, p = 0.002; Gamma Knife vs Cyberknife, p = 0.002).
CONCLUSIONS: The multiple focal entry systems (Gamma Knife and Cyberknife) achieve higher conformity than the Novalis system. The Gamma Knife delivers the steepest dose gradient of all examined systems. However, the Gamma Knife is known to require long beam-on times, and despite worse dose gradients, LINAC-based systems (Novalis and Cyberknife) offer image verification at the time of treatment delivery.
Pubmed
Web of science
Création de la notice
18/04/2015 12:25
Dernière modification de la notice
20/08/2019 13:08
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