2005 immunosuppressive strategies in kidney transplantation: which role for the calcineurin inhibitors?

Détails

ID Serval
serval:BIB_282F8019239D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
2005 immunosuppressive strategies in kidney transplantation: which role for the calcineurin inhibitors?
Périodique
Transplantation
Auteur(s)
Wong W., Venetz J.P., Tolkoff-Rubin N., Pascual M.
ISSN
0041-1337 (Print)
ISSN-L
0041-1337
Statut éditorial
Publié
Date de publication
08/2005
Volume
80
Numéro
3
Pages
289-296
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Résumé
The calcineurin inhibitors (CNIs) cyclosporine and tacrolimus have been the cornerstones of immunosuppressive strategies in clinical transplantation. Currently, regimens that are most widely used for induction and maintenance therapy include CNIs. However, many clinical trials aiming at reducing or eliminating CNIs have been performed in recent years. Here, we review and discuss current and future immunosuppressive strategies with a special emphasis on the role of CNIs, in the light of recent studies in the field of kidney transplantation. In the current era, CNIs still play an important role.
Mots-clé
Calcineurin/antagonists & inhibitors, Clinical Trials as Topic, Humans, Immunosuppressive Agents/therapeutic use, Kidney Transplantation/adverse effects, Kidney Transplantation/methods, Tacrolimus/pharmacology
Pubmed
Web of science
Création de la notice
29/01/2008 14:52
Dernière modification de la notice
20/08/2019 14:07
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